Pharmacovigilance
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Domestic
ATROPINE is a potent anticholinergic (parasympatholytic) drug. Its instillation to the eye produces pupil dilation or cycloplegic refraction, resulting mydriasis (increase of the size of pupil) and cycloplegia (blurred vision for close distance) of few days duration. It is applied as a mydriatic for therapeutic and rarely for diagnostic purposes and as cycloplegic for checking refractory disorders (skiascopy). It is used in acute and chronic inflammatory conditions of iris and uveal tract, independent of their aetiology. -
Domestic
DEXACHLOR contains a combination of two active substances, chloramphenicol which is an antimicrobial drug and dexamethasone which is a corticosteroid with anti-inflammatory activity. It is indicated in inflammatory conditions of the eye that respond to corticosteroids and in cases of bacterial contamination or possible risk of microbial contamination. Ophthalmic corticosteroids are indicated in the following cases: Symptomatic treatment of allergic conditions of the conjuctiva, the cornea and the eyelid, regardless of the causal allergen, inflammatory conditions of the sclera and episclera, as well as the cornea. They are also administered postoperative mainly for intraocular surgery, eye-ball injuries and corneoplastic surgery. It can be administered during infections from adenoviruses and common bacteria (conjunctivitis) in the early, intense phases of the inflammation, but under a general chemotherapy treatment. In general, they should be avoided in all infectious conditions of the eye. -
Domestic
PHENYLEPHRINE/COOPER contains a mydriatic agent. It is used to enlarge the pupil of your eye. Your doctor or eye specialist may use it to examine your eye more closely or as part of a treatment program. PHENYLEPHRINE/COOPER 5 % is indicated for children, adults and the elderly. PHENYLEPHRINE/COOPER 10% is not indicated for children or the elderly, as this concentration is too strong. The doctor or eye specialist will use an alternative medicine in these patients. -
Domestic
Pilocarpine is a parasympathomimetic drug which stimulates the cholinergic receptors. When applied topically pilocarpine produces constriction,stimutates the ciliary muscles and increase aqueous humor outflow facility. With the increase in outflow facility, there is a decrease in intraocular pressure (IOP). Miosis following topical application lasts 4-6 hours depending on th concentration of the solution. Pilocarpine may be used in compination with other miotics , beta blockers, carbonic anhydrates inhibitors, sympathomimetic agents. It is indicated in simple open-angle glaucoma, angle-closure glaucoma,chronic and acute.To achieve miosis, after mydriasis caused by mydriatic agents. -
Domestic
Naphazoline is a sympathomimetic drug which stimulates the α-adrenergic receptors. Instillation to the eye causes constriction of corneal vessels, inhibits hyperemia and creates to the patient a sense of immediate relief. Naphazoline in low concentrations is used in minor local eye irritations. SEPTOBORE combines the adrenergic action of naphazoline with the antiseptic substance boric acid. SEPTOBORE contains a special buffer solution and does not cause eye irritation. SEPTOBORE eye drops is indicated as decongestant for eye relief from the symptoms that accompany mild irritations of the conjunctiva caused by wind, dust, smoke, smog, swimming, contact lenses, eye-strain from reading, car driving or watching television. -
Domestic
Induces local anaesthesia for tonometry, removal of corneal foreign bodies, removal of sutures, operations at nasolachrymal duct, preparation for local injection of another medication, short procedures.
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