• Treatment of urinary tract infections from Escherichia coli , susceptible to
ampicillin.
• Infections due to Hemophilus influenza: pneumonia meningitis, exacerbations of chronic bronchitis, media ottitis, acute epiglottitis.
• Infections due to enterococci (Streptococcus fecalis): endocarditis
(in combination with an aminoglycoside), urinary tract infection.
• Typhoid fever (Salmonella Typhi) when the use of chloramphenicol or co-trimoxazole or quinolone is contraindicated (and since it is shown in vitro sensitivity)
• Infections from groups A & B streptococcus, such as tonsillitis, pneumonia and neonatal sepsis.
• Infections of newborns in combination with one of the aminoglycosides
• Pneumococcus infections (Streptococcus pneumoniae) e.g. pneumonia, acute media ottitis, meningitis. Ampicillin in high doses has been found capable of combating infections from moderately to susceptible penicillin strains of pneumococcus.